A cohort of patients diagnosed with essential hypertension was followed for 10 to 20 years to evaluate prognosis based on a four-grade classification of organic change.
Cohort
This paper summarizes the present status of a series of patients in whom essential hypertension was diagnosed from 10 to 12 or more years ago; no new patients have been added in the last 10 years. Two previous reports have been made on this series; one four years ago1and one six years ago.2Classification was originally made according to criteria previously outlined.2In brief, grade 1 included persons with minimal organic change, or none, as recognized by ordinary clinical examination in the three vital areas, head, heart, or kidneys; grade 2, those with definite or marked change, but no functional impairment; grade 3, those with organic change with functional impairment; and grade 4, those with papilledema. Classification was made according to maximum change found in any one or more areas without regard to elevation of blood pressure. A few patients were seen as long as 20
Robert S. Palmer (Sat,) conducted a cohort in Essential hypertension. A cohort of patients diagnosed with essential hypertension was followed for 10 to 20 years to evaluate prognosis based on a four-grade classification of organic change.