Key result
Hindlimb contraction in decerebrate cats caused a greater shortening of the R-R interval at high carotid sinus pressure (55 +/- 8 ms) than at low pressure (23 +/- 5 ms, P<0.001).
p-value: p=<0.001
Muscle contraction causes an immediate shortening of the R-R interval mediated by vagal withdrawal, an effect enhanced under conditions of high vagal tone.
No takes yet. Share an insight, caveat, or question.
Supports baroreflex modulation of vagal withdrawal during contraction; leaves open translation to human exercise physiology.
McMahon et al. (1992) studied Decerebrate cats (animal model) (n=13). Hindlimb contraction via electrical stimulation of L7 ventral roots vs. Low vs high carotid sinus pressure was evaluated on Change in R-R interval (p=<0.001). Hindlimb contraction in decerebrate cats caused a greater shortening of the R-R interval at high carotid sinus pressure (55 +/- 8 ms) than at low pressure (23 +/- 5 ms, P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: