Key result
Hybrid LV reconstruction linked to an ~11% LVEF increase and reduced volumes in ischemic HF.
Why the study?
LV remodeling after anterior myocardial infarction can cause increased LV volume, reduced EF, and symptomatic HF, prompting evaluation of midterm outcomes with hybrid transcatheter and minimally invasive LV reconstruction.
Does hybrid transcatheter and minimally invasive left ventricular reconstruction improve ejection fraction and symptoms in patients with ischemic heart failure?
Cohort (n=30)
No
Does hybrid transcatheter and minimally invasive left ventricular reconstruction improve ejection fraction and symptoms in patients with ischemic heart failure?
Absolute Event Rate: 44% vs 33%
p-value: p=<0.0001
Hybrid left ventricular reconstruction using the Revivent system significantly improves ejection fraction, reduces ventricular volumes, and improves symptoms in patients with ischemic heart failure.
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Supports feasibility in ischemic HF; leaves open confirmation of clinical benefit in randomized trials.
Hegeman et al. (2022) conducted a cohort in Ischemic Heart Failure (n=30). Hybrid left ventricular reconstruction (Revivent TransCatheter System) vs. Preoperative baseline was evaluated on Left ventricular ejection fraction (LVEF) (p=<0.0001). Hybrid left ventricular reconstruction using the Revivent TransCatheter System significantly increased LVEF from 33% to 44% (p<0.0001) and reduced LV volumes in patients with ischemic heart failure.
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