Key result
Intramyocardial dissecting hematoma carries ~23% in-hospital mortality, predicted by low EF, older age, and late diagnosis.
Why the study?
What are the clinical features and predictors of mortality in patients with intramyocardial dissecting hematoma?
Meta-Analysis (n=40)
What are the clinical features and predictors of mortality in patients with intramyocardial dissecting hematoma?
In patients with intramyocardial dissecting hematoma, in-hospital mortality is 23%, with low ejection fraction, older age, and late diagnosis serving as key predictors of death.
Answers are grounded in this paper and cite their sources.
High mortality warrants vigilance for low EF, older age, and late diagnosis in intramyocardial dissecting hematoma; leaves optimal management open.
Until recently, diagnosis of intramyocardial dissecting hematoma (IDH) was performed during necropsy or at surgery. During the recent years, echocardiography has permitted clinical suspicion, which usually needed confirmation with magnetic resonance imaging (MRI). In this study, we tried to define clinical and imaging features of IDH and predictors of mortality. We searched the literature for proven cases of IDH and analyzed them together with 2 of our cases. A total of 40 cases of IDH (2 our original and 38 literature cases) were included. Mean age was 60. In 32 cases, IDH was a complication of myocardial infarction (MI), in 66% anterior, a mean time from symptoms to diagnosis was 9 days. Thirty-eight % underwent surgery. In-hospital mortality was 23%. Multivariate analysis showed that the strongest independent predictor of mortality (42%) was EF < 35%; in patients with age >60, mortality risk was 44%; and in the presence of MI or late diagnosis (>24 hours since symptoms started), mortality risk was 50%. In summary, IDH is a diagnostic challenge. A high level of suspicion is needed for prompt diagnosis. Management of these patients is based on individual clinical and imaging parameters. Low EF, age > 60, and late diagnosis, all are predictors of in-hospital mortality.
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Leitman et al. (2018) conducted a meta-analysis in Intramyocardial dissecting hematoma (n=40). In a meta-analysis of 40 cases of intramyocardial dissecting hematoma, overall in-hospital mortality was 23%, with EF < 35%, age > 60, and late diagnosis identified as predictors of mortality.
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