Key result
Admission serum lactate predicts pediatric inpatient mortality with an AUC of 0.74.
Why the study?
The study was conducted to determine if serum lactate level at the time of hospital admission can predict mortality in pediatric patients.
Does serum lactate level at the time of hospital admission predict mortality in pediatric patients?
Meta-Analysis (n=2,099)
Does serum lactate level at the time of hospital admission predict mortality in pediatric patients?
Effect estimate: AUC 0.74 (95% CI 0.67-0.80)
p-value: p=< 0.01
Serum lactate at the time of admission is a valuable prognostic marker for identifying pediatric patients, including those undergoing cardiac surgery, at greater risk for inpatient mortality.
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May aid pediatric mortality risk stratification; confirms prognostic value of admission lactate across admissions.
Loomba et al. (2022) conducted a meta-analysis in Pediatric admissions (n=2,099). Serum lactate at admission was evaluated on Inpatient mortality (AUC 0.74, 95% CI 0.67-0.80, p=< 0.01). Serum lactate level at hospital admission significantly predicted inpatient mortality in pediatric patients, with a pooled area under the curve of 0.74 (95% CI 0.67-0.80; p<0.01).