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September 1, 2017MedicineOpen Access

Risk analysis of dialysis-dependent patients who underwent coronary artery bypass grafting

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Key result

Peritoneal dialysis linked to ~20-fold higher odds of in-hospital mortality versus hemodialysis after CABG.

  • OR 19.607
  • 95% CI 3.676-104.589
  • P<.001
  • n=134

Why the study?

Does peritoneal dialysis compared to hemodialysis affect in-hospital mortality and 1-year survival in dialysis-dependent patients undergoing CABG?

Population

134 dialysis-dependent patients who underwent coronary artery bypass grafting from October 2005 to January…

Comparison

Peritoneal dialysis (PD) prior to CABG vs Hemodialysis (HD) prior to CABG

Design

Cohort

Follow-up

In-hospital and 1 year

Authors

HLHan-Yan LiKeelung Chang Gung Memorial HospitalCCChih‐Hsiang ChangNational Health Research InstitutesCLCheng‐Chia LeeChang Gung University

Discussion

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Member takes

Implication

Warrants caution with peritoneal dialysis in dialysis-dependent CABG patients; leaves open whether selection bias or causation drives the association.

Study Design

Type

Observational (n=134)

Structured PICO

Does peritoneal dialysis compared to hemodialysis affect in-hospital mortality and 1-year survival in dialysis-dependent patients undergoing CABG?

P
Population
134 dialysis-dependent patients who underwent coronary artery bypass grafting (CABG) from October 2005 to January 2015
I
Intervention
Peritoneal dialysis (PD) prior to CABG
C
Comparator
Hemodialysis (HD) prior to CABG
O
Outcome
In-hospital mortalityhard clinical

Main Result

Effect estimate: OR 19.607 (95% CI 3.676-104.589)

Absolute Event Rate: 58.3% vs 14.8%

p-value: p=< .001

Peritoneal dialysis, older age, previous stroke, and emergent operation are significant risk factors for in-hospital mortality in dialysis-dependent patients undergoing CABG.

Cite This Study

Li et al. (2017) conducted an observational in Dialysis-dependent patients undergoing CABG (n=134). Peritoneal dialysis vs. Hemodialysis was evaluated on In-hospital mortality (OR 19.607, 95% CI 3.676-104.589, p=< .001). Among dialysis-dependent patients undergoing CABG, peritoneal dialysis was associated with significantly higher in-hospital mortality compared to hemodialysis (58.3% vs 14.8%; OR 19.607, P<0.001).

synapsesocial.com/papers/6a0d9d3ccae7912d2fa5200ehttps://doi.org/10.1097/md.0000000000008146

Topics

Coronary artery disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiac, Inflammatory and Metabolic Parameters: Hemodialysis versus Peritoneal Dialysis2014 · 27 citations
  2. 2Comparing Cardiac Surgery in Peritoneal Dialysis and Hemodialysis Patients: Perioperative Outcomes and Two-Year Survival2011 · 28 citations
  3. 3ACC/AHA guidelines for coronary artery bypass graft surgery1999 · 1,997 citations
  4. 4Risks of Morbidity and Mortality in Dialysis Patients Undergoing Coronary Artery Bypass Surgery2000 · 216 citations
  5. 5Cardiac Surgery in Patients on Chronic Hemodialysis: Short and Long-Term Survival2008 · 30 citations