Key result
Hemodialysis-dependent patients undergoing isolated CABG had lower 3-year survival compared to non-hemodialysis controls (90.6% vs 97.6%, P<0.001).
Why the study?
Does isolated CABG have different perioperative and long-term outcomes in hemodialysis-dependent patients compared to non-hemodialysis patients?
Population
1,676 patients undergoing isolated coronary artery bypass grafting, including 37 hemodialysis-dependent…
Comparison
Isolated coronary artery bypass grafting in… vs Isolated CABG in non-hemodialysis control patients
Design
Cohort
Follow-up
mean 2.4 years
Authors
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HD patients face higher post-CABG mortality; leaves open whether targeted perioperative strategies narrow survival gaps.
Cohort (n=1,676)
No
Does isolated CABG have different perioperative and long-term outcomes in hemodialysis-dependent patients compared to non-hemodialysis patients?
Absolute Event Rate: 90.6% vs 97.6%
p-value: p=<0.001
CABG in hemodialysis-dependent patients carries higher perioperative risks and lower long-term overall survival, but provides similar long-term freedom from cardiac events compared to non-hemodialysis patients.
Hirose et al. (2001) conducted a cohort in Coronary atherosclerosis requiring CABG (n=1,676). Hemodialysis dependence vs. Control patients (not on hemodialysis) was evaluated on Actuarial 3-year survival (excluding hospital mortality) (p=<0.001). Hemodialysis-dependent patients undergoing isolated CABG had lower 3-year survival compared to non-hemodialysis controls (90.6% vs 97.6%, P<0.001).
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