Key result
This review summarizes the biogenesis, trafficking, and assembly of potassium channel multi-subunit complexes in the endoplasmic reticulum and their transport to the cell surface.
Design
Review
Authors
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Should not yet change arrhythmia management; extends foundational knowledge of channel trafficking for future research.
This review provides a comprehensive overview of the molecular mechanisms governing potassium channel formation and trafficking, which are fundamental to cellular electrical activity.
Carol Deutsch (2002) conducted a review in Potassium channel ontogeny. This review summarizes the biogenesis, trafficking, and assembly of potassium channel multi-subunit complexes in the endoplasmic reticulum and their transport to the cell surface.
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