Key result
Synthesized aorta pressure waves yielded central systolic blood pressure estimates in good agreement with carotid tonometry (r=0.97), but correlation for augmentation index was relatively poor (r=0.75).
Why the study?
Does synthesized aorta pressure waveform estimation provide interchangeable values for central SBP and AIx compared to carotid tonometry in adult subjects?
Population
276 subjects (179 men/97 women; mean age 45.5 +/- 5.7 years)
Comparison
Synthesized aorta pressure waveforms derived… vs Carotid tonometry
Design
Cross-sectional
Authors
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Synthesized aortic waveforms may support central SBP estimation in observational cohorts; leaves open AIx interchangeability pending prospective validation.
Cross-Sectional (n=276)
Does synthesized aorta pressure waveform estimation provide interchangeable values for central SBP and AIx compared to carotid tonometry in adult subjects?
Effect estimate: r = 0.97 (SBP), r = 0.75 (AIx)
p-value: p=<.001
Synthesized aortic pressure waveforms provide accurate estimates of central systolic blood pressure compared to carotid tonometry, but are less reliable for estimating augmentation index.
Segers et al. (2005) reported a cross-sectional. Synthesized aorta pressure waves vs. Carotid tonometry was evaluated on Interchangeability for estimating central systolic blood pressure (SBP) and augmentation index (AIx) (r = 0.97 (SBP), r = 0.75 (AIx), p=<.001). Synthesized aorta pressure waves yielded central systolic blood pressure estimates in good agreement with carotid tonometry (r=0.97), but correlation for augmentation index was relatively poor (r=0.75).
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