Why the study?
Left ventricular hypertrophy is a common manifestation of cardiovascular disease and a risk factor for morbidity and mortality, but available electrocardiographic diagnostic methods have limited accuracy.
Does a newly derived 5-criteria ECG scoring system improve the diagnostic accuracy of left ventricular hypertrophy compared to conventional criteria in outpatients?
Population
5486 derivation outpatients and 910 validation patients with ECGs within 30 days of TTE
Comparison
Newly derived 5-criteria ECG score vs established criteria for LVH
Design
Cohort study
Key result
A newly derived 5-criteria ECG scoring system for detecting left ventricular hypertrophy achieved 62.5% sensitivity and 83.2% specificity at a 1.5-point threshold in an independent validation cohort.
Authors
Loading...
May support ECG-based LVH detection in outpatients but should not yet change practice; leaves open head-to-head validation against conventional criteria.
Cohort (n=6,396)
Does a newly derived 5-criteria ECG scoring system improve the diagnostic accuracy of left ventricular hypertrophy compared to conventional criteria in outpatients?
A novel 5-criteria ECG scoring system improves sensitivity for detecting left ventricular hypertrophy compared to conventional criteria, with only a modest decrease in specificity.
Braunstein et al. (2019) conducted a cohort in Left ventricular hypertrophy (LVH) (n=6,396). New 5-criteria ECG scoring system vs. Established criteria for LVH was evaluated on Detection of LVH by ECG. A newly derived 5-criteria ECG scoring system for detecting left ventricular hypertrophy achieved 62.5% sensitivity and 83.2% specificity at a 1.5-point threshold in an independent validation cohort.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: