Why the study?
Small blood pressure reductions lower vascular disease risk even in normotensive ranges, but the efficacy and safety of calcium supplementation to reduce blood pressure and prevent hypertension required updated evaluation.
Does calcium supplementation reduce blood pressure and prevent primary hypertension in normotensive individuals?
Population
3512 normotensive participants across 20 trials
Comparison
Dietary calcium interventions (supplementation or fortification) vs placebo or control
Design
Systematic review and meta-analysis of randomised controlled trials
Authors
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Supports adjunctive calcium for hypertension prevention in normotensives; confirms modest BP reductions with high-certainty evidence.
Does calcium supplementation reduce blood pressure and prevent primary hypertension in normotensive individuals?
Calcium supplementation provides a small but statistically significant reduction in systolic and diastolic blood pressure in normotensive individuals, suggesting a potential role in the prevention of primary hypertension.
Cormick et al. (2021) studied this question.
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