Key result
Adequate control of arterial pressure slows renal disease progression, with ACE inhibitors and their combination with calcium antagonists potentially affording more nephroprotection than other agents.
Why the study?
Do specific antihypertensive drugs provide nephroprotection beyond blood pressure reduction in patients with essential hypertension?
Population
Patients with essential hypertension
Comparison
Antihypertensive drugs vs Other antihypertensive agents or different…
Design
Review
Authors
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BP control slows renal progression in essential hypertension; leaves open whether ACE inhibitor combinations add nephroprotection beyond BP lowering.
Do specific antihypertensive drugs provide nephroprotection beyond blood pressure reduction in patients with essential hypertension?
This review highlights that while lowering blood pressure is crucial for slowing renal disease progression in essential hypertension, ACE inhibitors may offer additional nephroprotective benefits.
Sušić et al. (1998) conducted a review in Essential hypertension. Antihypertensive drugs (ACE inhibitors, calcium antagonists) vs. Other antihypertensive agents was evaluated on Progression of hypertension-related renal disease. Adequate control of arterial pressure slows renal disease progression, with ACE inhibitors and their combination with calcium antagonists potentially affording more nephroprotection than other agents.
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