Key result
Diastolic blood pressures of 85 to 104 mm Hg were associated with increased total death rate, coronary deaths, major coronary events, and cerebrovascular episodes over 10 years.
Why the study?
Does mild hypertension (diastolic blood pressure 85-104 mm Hg) increase the risk of cardiovascular morbidity and mortality in men aged 30 to 59?
Cohort (n=6,640)
Yes
Does mild hypertension (diastolic blood pressure 85-104 mm Hg) increase the risk of cardiovascular morbidity and mortality in men aged 30 to 59?
Mild elevations in diastolic blood pressure (85-104 mm Hg) are associated with significantly increased risks of cardiovascular morbidity and all-cause mortality over 10 years in adult men.
Mild diastolic hypertension was associated with higher CV risk; leaves open whether treatment improves outcomes in men aged 30-59.
Data relating to the risks of hypertension are presented from six prospective studies of cardiovascular disease initiated in the United States 1948-1958. 6640 men, aged 30 to 59 when first seen, were followed for 10 years and observations recorded on morbidity from cardiovascular disease and mortality from all causes as well as from cardiovascular disease. Diastolic blood pressures of 85 to 104 mm. Hg as recorded on the initial visit have unfavourable implications in terms of total death rate, deaths from coronary disease, major coronary events (non-fatal myocardial infarctions and deaths from coronary disease), and cerebrovascular episodes. The deleterious effect is most conspicuous in men in their fifties, but also appears in the younger age groups.
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O Paul (1971) conducted a cohort in Mild hypertension (n=6,640). Diastolic blood pressure 85-104 mm Hg was evaluated on Morbidity from cardiovascular disease and mortality from all causes and cardiovascular disease. Diastolic blood pressures of 85 to 104 mm Hg were associated with increased total death rate, coronary deaths, major coronary events, and cerebrovascular episodes over 10 years.
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