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August 30, 2005CirculationOpen Access

Progression of Tricuspid Regurgitation After Repaired Functional Ischemic Mitral Regurgitation

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Why the study?

Does functional tricuspid regurgitation progress over time after successful mitral valve repair for functional ischemic mitral regurgitation?

Population

70 patients who underwent successful revascularization and mitral valve repair for functional ischemic…

Design

Cohort

Follow-up

Up to >3 years

Key result

After mitral valve repair for functional ischemic mitral regurgitation, 49% of patients had significant tricuspid regurgitation at follow-up, with incidence increasing to 74% at >3 years.

Authors

AMAkira MatsunagaCDCarlos M.G. Durán

Discussion

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Overview

Warrants closer TR surveillance after mitral repair; leaves open whether concomitant intervention improves outcomes.

Study Design

Type

Cohort (n=70)

Structured PICO

Does functional tricuspid regurgitation progress over time after successful mitral valve repair for functional ischemic mitral regurgitation?

P
Population
70 patients who underwent successful revascularization and mitral valve repair (MVRep) for functional ischemic mitral regurgitation (MR), leaving the operating room with MR ≤1+ and having preoperative and follow-up transthoracic echocardiograms (from an initial cohort of 124 consecutive patients).
I
Intervention
Mitral valve repair and revascularization (with or without tricuspid valve repair)
O
Outcome
Incidence and progression of significant (moderate or greater) tricuspid regurgitation at follow-upsurrogate

Main Result

Absolute Event Rate: 44% vs 67%

Close to 50% of patients develop significant tricuspid regurgitation after successful mitral valve repair for functional ischemic MR, with the incidence increasing over time and predicted by preoperative tricuspid annulus dilation.

Cite This Study

Matsunaga et al. (2005) conducted a cohort in Functional ischemic mitral regurgitation (n=70). Tricuspid valve repair vs. Surgically ignored tricuspid valve was evaluated on Residual tricuspid regurgitation. After mitral valve repair for functional ischemic mitral regurgitation, 49% of patients had significant tricuspid regurgitation at follow-up, with incidence increasing to 74% at >3 years.

synapsesocial.com/papers/6a0dfc83e119ff9c3ed6bc80https://doi.org/10.1161/circulationaha.104.524421
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tricuspid regurgitation secondary to mitral valve disease Tricuspid annulus function as guide to tricuspid valve repair2001 · 131 citations
  2. 2Mechanism of Recurrent Ischemic Mitral Regurgitation After Annuloplasty2004 · 435 citations
  3. 3Insights From Three-Dimensional Echocardiography Into the Mechanism of Functional Mitral Regurgitation1997 · 593 citations