Key result
Preoperative atrial fibrillation predicted progression to severe tricuspid regurgitation in patients who did not undergo concomitant tricuspid valve annuloplasty during mitral valve repair.
Why the study?
Does concomitant tricuspid valve annuloplasty prevent progression to severe TR and improve outcomes in patients undergoing mitral valve repair for degenerative mitral regurgitation?
Cohort (n=654)
No
Does concomitant tricuspid valve annuloplasty prevent progression to severe TR and improve outcomes in patients undergoing mitral valve repair for degenerative mitral regurgitation?
Concomitant tricuspid valve annuloplasty should be considered during mitral valve repair for degenerative MR in patients with atrial fibrillation and moderate or greater TR to prevent progression to severe TR.
Answers are grounded in this paper and cite their sources.
Preoperative AF may flag higher TR progression risk after mitral repair without annuloplasty; leaves open whether routine concomitant annuloplasty improves outcomes.
BACKGROUND: The issue of whether functional tricuspid regurgitation (TR) should be repaired at the time of mitral valve surgery is controversial, and the long-term durability of tricuspid valve (TV) annuloplasty remains unknown. METHODS AND RESULTS: We retrospectively reviewed 654 patients who underwent mitral valve repair for degenerative mitral regurgitation between 1991 and 2010. Preoperative TR was classed as mild, trivial or absent in 479 (73.2%) patients, moderate in 125 (19.1%) patients and severe in 50 (7.7%) patients. Concomitant TV annuloplasty was performed in 162 patients (24.8%). The mean follow up duration was 7.5±4.9 years. Postoperative transthoracic echocardiography was performed according to a fixed schedule. The long-term survival rate and freedom from re-admission for congestive heart failure were affected by the severity of TR. Although the durability of ring annuloplasty was excellent up to 10 years after surgery, the mean TR grade started to increase after 10 years. Sixteen out of 492 patients who did not undergo TV annuloplasty (3.2%) revealed progression to severe TR. Preoperative atrial fibrillation (odds ratio (OR), 4.85; 95% confidence interval (CI), 1.38-17.1; P=0.014) and preoperative TR grade (OR, 5.16; 95% CI, 1.78-14.9; P=0.003) were predictors for progression to severe TR. CONCLUSIONS: Aggressive treatment with concomitant TV annuloplasty should be advocated in cases with atrial fibrillation and more than moderate TR.
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Murashita et al. (2013) conducted a cohort in Degenerative mitral regurgitation with functional tricuspid regurgitation (n=654). Preoperative atrial fibrillation vs. Absence of preoperative atrial fibrillation was evaluated on Progression to severe tricuspid regurgitation in patients without concomitant tricuspid valve repair (OR 4.85, 95% CI 1.38-17.1, p=0.014). Preoperative atrial fibrillation predicted progression to severe tricuspid regurgitation in patients who did not undergo concomitant tricuspid valve annuloplasty during mitral valve repair.
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