Key result
Tricuspid valve replacement with mitral homograft yields 0% 30-day mortality and excellent early hemodynamics.
Why the study?
The authors sought to present the immediate results of tricuspid valve replacement using a mitral homograft.
Does tricuspid valve replacement with mitral homograft provide safe early clinical and hemodynamic outcomes in patients with tricuspid insufficiency?
Observational (n=21)
Yes
Does tricuspid valve replacement with mitral homograft provide safe early clinical and hemodynamic outcomes in patients with tricuspid insufficiency?
Tricuspid valve replacement with a mitral homograft demonstrates excellent early hemodynamic results and no 30-day mortality, suggesting it is a viable alternative valve substitute.
Supports safe early outcomes with mitral homograft; leaves open need for prospective validation before wider use.
Objective. To present the immediate results of tricuspid valve replacement with mitral homograft. Material and methods. We enrolled 21 patients who underwent surgery between September 2021 and April 2023 in 2 departments. Etiology of tricuspid insufficiency: infective (including prosthetic) endocarditis — 16 (76%), tumor thrombosis of inferior vena cava — 1 (5%), congenital heart disease — 2 (9%), bioprosthesis failure — 1 (5%), thrombosis of mechanical prosthesis — 1 (5%). There were 5 (24%) redo surgeries. All patients underwent tricuspid valve replacement with mitral homograft. We estimated intraoperative and early postoperative results, as well as primary endpoints. Results. Aortic cross-clamping and cardiopulmonary bypass time was 118.1±23.7 and 145.1±26.9 min, respectively. Concomitant procedures were performed in 4 patients. Postoperative complications included 2 (9.5%) cases of permanent pacemaker implantation, 3 (14.2%) cases of pneumonia. There were no 30-day mortality and other complications. Maximum and mean pressure gradient was 5 [5; 8] and 3 [2; 4] mm Hg. There were no significant changes in right and left ventricular systolic function after tricuspid valve replacement with homograft. Conclusion. We revealed excellent early hemodynamic and clinical results in tricuspid valve surgery with mitral homograft without significant changes in ventricular systolic function. Mitral homograft may be recommended as an alternative valve substitute in appropriate patients.
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Nuzhdin et al. (2024) conducted an observational in Tricuspid insufficiency (n=21). Tricuspid valve replacement with mitral homograft was evaluated on 30-day mortality. Tricuspid valve replacement with mitral homograft in 21 patients resulted in 0% 30-day mortality and excellent early hemodynamics without significant changes in ventricular systolic function.
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