Key result
Eleven-parameter risk score accurately predicts 1-year mortality in significant TR.
Why the study?
Most patients with significant tricuspid regurgitation are treated conservatively, but individual mortality rates are markedly variable.
Can a clinical and echocardiographic risk score predict 1-year mortality in patients with significant tricuspid regurgitation treated conservatively?
Cohort (n=6,842)
Can a clinical and echocardiographic risk score predict 1-year mortality in patients with significant tricuspid regurgitation treated conservatively?
Effect estimate: AUC 0.78
A novel 11-parameter risk score accurately predicts 1-year mortality in patients with significant tricuspid regurgitation managed conservatively, aiding in risk stratification.
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May aid risk stratification in conservatively managed significant TR; leaves open prospective validation and outcome impact.
Hochstadt et al. (2022) conducted a cohort in Significant tricuspid regurgitation (n=6,842). 11-parameter risk score vs. Matched patients without significant TR was evaluated on 1-year mortality (AUC 0.78). An 11-parameter risk score accurately predicted 1-year mortality in patients with significant tricuspid regurgitation, yielding an AUC of 0.78 in the derivation and 0.70 in the validation cohort.
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