Key result
Fontan-type surgery in patients with univentricular hearts resulted in similar peak oxygen consumption compared to cyanotic patients without corrective surgery (21.0 vs 21.7 ml/kg/min, P=0.85).
Why the study?
Does the Fontan procedure improve exercise tolerance and reduce dyspnoea during cardiopulmonary exercise testing in patients with univentricular heart compared to palliative or no surgery?
Population
18 patients with univentricular heart and 10 healthy age-matched subjects.
Comparison
Fontan-type procedure vs Palliative or no surgery
Design
Cross-sectional
Authors
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May not enhance exercise tolerance over palliation in univentricular hearts; leaves open mechanisms and long-term functional outcomes.
Cross-Sectional (n=28)
Does the Fontan procedure improve exercise tolerance and reduce dyspnoea during cardiopulmonary exercise testing in patients with univentricular heart compared to palliative or no surgery?
Absolute Event Rate: 21% vs 21.7%
p-value: p=0.85
Despite improving arterial oxygenation, the Fontan procedure does not appear to significantly improve peak exercise tolerance or exertional dyspnoea compared to chronic hypoxaemia in patients with univentricular hearts.
Iserin et al. (1997) conducted a cross-sectional in Univentricular heart (n=28). Fontan-type procedure vs. Palliative or no surgery (cyanotic) was evaluated on Peak oxygen consumption (ml.kg-1.min-1) (p=0.85). Fontan-type surgery in patients with univentricular hearts resulted in similar peak oxygen consumption compared to cyanotic patients without corrective surgery (21.0 vs 21.7 ml/kg/min, P=0.85).
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