Relation of blood pressure, serum lipids, and smoking to the risk of cerebral stroke. A longitudinal study in Eastern Finland.
Why the study?
Are blood pressure, serum lipids, and smoking associated with the risk of cerebral stroke in adults aged 35-59?
Population
Random sample of the population aged 35-59 years in two counties of Eastern Finland
Design
Cohort
Follow-up
7 years
Authors
Discussion
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Implication
Does not support changing BP targets; leaves open causality and optimal thresholds for randomized confirmation.
Key Points
- The study aims to explore how blood pressure, serum lipids, and smoking contribute to the risk of cerebral stroke.
- Longitudinal design conducted on a random sample aged 35-59 years in Eastern Finland.
- Data collected included blood pressure, serum lipid levels, and smoking habits.
- Participants were followed for seven years using hospital discharge and death certificate registers.
- 77 men and 65 women experienced a cerebral stroke during follow-up.
- Diastolic blood pressure of 100 mm Hg or higher was linked to a 1.9-fold increased risk for men and 2.5-fold for women without previous strokes.
- In men, 37% of strokes were attributable to systolic blood pressure of 150 mm Hg or more.
Structured PICO
Are blood pressure, serum lipids, and smoking associated with the risk of cerebral stroke in adults aged 35-59?
P
Population
Random sample of the population aged 35-59 years in two counties of Eastern Finland
O
Outcome
Cerebral infarction and other strokehard clinical
Elevated blood pressure, smoking, and history of diabetes or previous stroke are independent predictors of cerebral stroke in middle-aged adults.
Cite This Study
Salonen et al. (1982) studied this question.