Key result
Pacemaker implantation had little discernible effect on mortality in a 10-year prospective survey of 381 patients with sinoatrial dysfunction, though it reduced incapacitating symptoms.
Why the study?
Does pacemaker implantation improve survival in patients with sinoatrial dysfunction?
Cohort (n=381)
Does pacemaker implantation improve survival in patients with sinoatrial dysfunction?
Sinoatrial dysfunction is a relatively benign condition where pacemaker implantation does not significantly improve survival but can reduce incapacitating symptoms.
Answers are grounded in this paper and cite their sources.
Pacemaker implantation should target symptoms, not survival, in sinoatrial dysfunction; observational data leave open need for randomized confirmation.
A total of 381 patients with established (156) or potential (225) sinoatrial dysfunction were included in a 10-year prospective survey to determine the course of the disease and the benefits of pacing. With the exclusion of nine patients who were lost to follow-up, 61 were fitted with pacemakers. The overall survival of patients with established and potential dysfunction was similar and apparently indistinguishable from that of the normal population. Pacemaker implantation had little discernible effect on mortality though it reduced some incapacitating symptoms. These findings suggest that sinoatrial dysfunction is a relatively benign condition. Hence pacing should probably not be adopted as a routing measure but be reserved for patients with troublesome symptoms.
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Shaw et al. (1980) conducted a cohort in sinoatrial disorder (sick-sinus syndrome) (n=381). Pacemaker implantation vs. No pacemaker was evaluated on Overall survival. Pacemaker implantation had little discernible effect on mortality in a 10-year prospective survey of 381 patients with sinoatrial dysfunction, though it reduced incapacitating symptoms.
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