Comparison of M-mode and cross-sectional echocardiography in infective endocarditis.
Key result
Cross-sectional and M-mode echocardiography identified vegetations in 82.6% and 78.3% of patients with infective endocarditis, respectively, but vegetation features did not predict clinical events.
Why the study?
Does cross-sectional echocardiography improve the identification of vegetations compared to M-mode echocardiography in patients with infective endocarditis?
Population
23 consecutive patients with infective endocarditis
Comparison
Cross-sectional echocardiography vs M-mode echocardiography
Design
Cohort
Follow-up
1 month
Authors
Discussion
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Member takes
Implication
Cross-sectional echocardiography offers no diagnostic advantage over M-mode for vegetation detection in infective endocarditis; hypothesis-generating for lack of prognostic utility.
Key Points
- To compare the diagnostic utility and prognostic value of M-mode and cross-sectional echocardiography in identifying vegetations and anticipating early clinical complications in infective endocarditis.
- Conducted both cross-sectional and M-mode echocardiograms on N=23 consecutive patients diagnosed with infective endocarditis.
- Evaluated vegetation detection rates across both modalities and assessed whether vegetation size and shape correlated with early valve replacement within 1 month or major peripheral emboli.
- Both M-mode and cross-sectional echocardiography identified vegetations in 18 of 23 patients, while 5 patients had no vegetations detected by either method.
- Cross-sectional echocardiography uniquely detected a vegetation in one patient with a prosthetic valve.
- Ten patients with detected vegetations required valve replacement within 1 month, but vegetation size and shape on cross-sectional imaging did not accurately predict early surgery or major peripheral emboli.
Study Design
Type
Cross-Sectional (n=23)
Structured PICO
Does cross-sectional echocardiography improve the identification of vegetations compared to M-mode echocardiography in patients with infective endocarditis?
P
Population
23 consecutive patients with infective endocarditis
I
Intervention
Cross-sectional echocardiography
C
Comparator
M-mode echocardiography
O
Outcome
Identification of vegetationssurrogate
Main Result
Absolute Event Rate: 82.6% vs 78.3%
Cross-sectional echocardiography provides similar diagnostic yield to M-mode for detecting vegetations in infective endocarditis, but vegetation characteristics do not predict clinical complications.
Cite This Study
Wann et al. (1979) conducted a cross-sectional in infective endocarditis (n=23). Cross-sectional echocardiography vs. M-mode echocardiography was evaluated on Identification of vegetations. Cross-sectional and M-mode echocardiography identified vegetations in 82.6% and 78.3% of patients with infective endocarditis, respectively, but vegetation features did not predict clinical events.