Key result
Low-dose dobutamine stress echocardiography is a safe and widely available modality that can accurately predict the improvement of dysfunctional yet viable myocardial regions following revascularization.
Why the study?
Does low-dose dobutamine stress echocardiography accurately identify myocardial viability and predict functional improvement following revascularization in patients with ischemic LV dysfunction?
Does low-dose dobutamine stress echocardiography accurately identify myocardial viability and predict functional improvement following revascularization in patients with ischemic LV dysfunction?
Dobutamine stress echocardiography is a safe, widely available, and relatively inexpensive modality for identifying myocardial viability and predicting LV functional recovery after revascularization.
Answers are grounded in this paper and cite their sources.
Supports viability assessment with low-dose DSE in ischemic LV dysfunction; leaves open randomized outcome trials.
The noninvasive assessment of myocardial viability has proved clinically useful for distinguishing hibernating and/or stunned myocardium from irreversibly injured myocardium in patients with chronic ischemic heart disease or recent myocardial infarction, with marked regional and/or global left ventricular (LV) dysfunction. Noninvasive techniques utilized for the detection of viability in asynergic myocardial regions include positron emission tomographic imaging of residual metabolic activity, single photon emission tomography (SPECT) of radioisotope uptake with thallium-201, low-dose dobutamine echocardiography assessment of inotropic reserve and myocardial contrast echocardiography for evaluation of microvascular integrity. Of these techniques, dobutamine stress echocardiography is a safe, widely available and relatively inexpensive modality for the identification of myocardial viability for risk stratification and prognosis. Low-dose dobutamine response can accurately predict improvement of dysfunctional yet viable myocardial regions, and thus identify a subset of patients whose LV function will improve following successful coronary revascularization.
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Yao et al. (2005) conducted a review in Ischemic Left Ventricular Dysfunction. Dobutamine Stress Echocardiography was evaluated on Prediction of improvement of dysfunctional yet viable myocardial regions following successful coronary revascularization. Low-dose dobutamine stress echocardiography is a safe and widely available modality that can accurately predict the improvement of dysfunctional yet viable myocardial regions following revascularization.
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