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July 24, 2018Diabetes and Vascular Disease ResearchOpen Access

The prevalence of left ventricular diastolic dysfunction and heart failure with preserved ejection fraction in men and women with type 2 diabetes: A systematic review and meta-analysis

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Population

Type 2 diabetes patients from 28 studies.

Design

Meta-analysis

Authors

SBSelma H. BouthoornGVGideon ValstarAGAisha Gohar

Discussion

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Overview

Diastolic dysfunction warrants clinical vigilance in type 2 diabetes; confirms high, sex-independent prevalence across settings.

Structured PICO

P
Population
Type 2 diabetes patients from 28 studies (2959 in hospital population and 2813 in general population for left ventricular diastolic dysfunction analysis).
O
Outcome
Prevalence of left ventricular diastolic dysfunction or heart failure with preserved ejection fraction

Left ventricular diastolic dysfunction is highly prevalent in patients with type 2 diabetes, affecting nearly half of hospitalized patients and over a third of the general diabetic population, with similar rates in men and women.

Limitations

  • High heterogeneity in both populations (estimates ranging from 19% to 81% in hospital and 23% to 54% in general population)
  • Only two studies presented the prevalence of heart failure with preserved ejection fraction

Cite This Study

Bouthoorn et al. (2018) studied this question.

synapsesocial.com/papers/6a0e4f752856274882078832https://doi.org/10.1177/1479164118787415
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