Key result
Early repolarization pattern links to increased intra-left atrial electromechanical delay despite preserved phasic functions.
Why the study?
Atrial electromechanical delay and left atrial phasic function predict atrial fibrillation, but their status in individuals with electrocardiographic early repolarization pattern had not been evaluated.
Does the presence of electrocardiographic early repolarization pattern affect atrial electromechanical delay and left atrial phasic function?
Cross-Sectional (n=120)
Does the presence of electrocardiographic early repolarization pattern affect atrial electromechanical delay and left atrial phasic function?
Individuals with an early repolarization pattern have increased intra-left atrial electromechanical delay but preserved left atrial phasic function, which may have implications for atrial fibrillation susceptibility.
Answers are grounded in this paper and cite their sources.
May warrant atrial arrhythmia surveillance in early repolarization; leaves open independent AF prediction.
BACKGROUND: Atrial electromechanical delay (EMD) and left atrial (LA) phasic function have been demonstrated to be predictors for the development of atrial fibrillation (AF). In the present study, we aimed to evaluate atrial EMD and LA phasic function in individuals with electrocardiographic early repolarization pattern (ERP). METHODS: Eighty consecutive individuals with ERP and 40 age- and gender-matched control subjects without ERP were compared in this cross-sectional study. Atrial electromechanical coupling (Pa′) was measured from lateral mitral annulus (Pa′(lateral)), septal mitral annulus (Pa′(septal)), and lateral tricuspid annulus (Pa′(tricuspid)) using tissue Doppler echocardiography to calculate intra- and inter-atrial EMD. LA maximal volume, LA minimal volume, and LA volume before atrial contraction were calculated using the biplane area-length method to assess LA phasic function. RESULTS: LA diameter, LA volume index, Pa′(lateral), Pa′(septal), Pa′(tricuspid) electrical activity and intra-left atrial EMD were significantly increased in the ERP patients. Mitral lateral, septal, tricuspid lateral annular tissue Doppler s′ and e′ waves were significantly decreased in the ERP patients. There were no significant difference between the groups in terms of interatrial EMD, intra-right atrial EMD, LA total emptying volume and LA total emptying fraction indicating LA reservoir function, LA passive emptying volume and LA passive emptying fraction indicating LA conduit function, LA active emptying volume and LA active emptying fraction indicating LA pump function. CONCLUSIONS: Left atrial EMD parameters are affected in individuals with ERP, but LA phasic functions are not affected. Further prospective studies are needed to clarify whether individuals with ERP have an increased susceptibility to AF.
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Akçay et al. (2022) conducted a cross-sectional in Electrocardiographic early repolarization pattern (n=120). Electrocardiographic early repolarization pattern vs. Controls without early repolarization pattern was evaluated on Atrial electromechanical delay and left atrial phasic function. Early repolarization pattern was associated with significantly increased intra-left atrial electromechanical delay compared to controls, while left atrial phasic functions remained unaffected.
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