Key result
Left ventricular diastolic dysfunction, indicated by a higher E/Em ratio, was independently associated with impaired left atrial mechanical function (β=-0.20, P=0.013) in paroxysmal AF.
Population
286 patients with non-valvular paroxysmal atrial fibrillation (PAF), mean age 57 ± 11 years, 73% male.
Design
Cross-sectional
Authors
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Links LV diastolic dysfunction to LA impairment in paroxysmal AF; hypothesis-generating, should not yet change practice.
Observational (n=286)
Absolute Event Rate: 10.3% vs 9.2%
p-value: p=0.034
In patients with non-valvular paroxysmal AF, impaired LV diastolic function is independently associated with reduced left atrial mechanical function and electroanatomical remodeling.
Lee et al. (2012) conducted an observational in Non-valvular paroxysmal atrial fibrillation (n=286). Impaired LA mechanical function (LAA-FV <58 cm/s) vs. Preserved LA mechanical function (LAA-FV ≥ 58 cm/s) was evaluated on E/Em ratio (p=0.034). Left ventricular diastolic dysfunction, indicated by a higher E/Em ratio, was independently associated with impaired left atrial mechanical function (β=-0.20, P=0.013) in paroxysmal AF.
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