Key result
Patients with atrial fibrillation and pulmonary venous hypertension had markedly reduced left atrial filling fraction (11.4% vs 111.5%, p<0.0001) compared to those with pulmonary arterial hypertension.
Population
Patients with atrial fibrillation, severe left atrial enlargement, and pulmonary venous hypertension…
Design
Cross-sectional
Authors
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Should not alter AF-PVH management; hypothesis-generating for LA diastolic dysfunction in HFpEF pathophysiology.
Observational (n=15)
No
Absolute Event Rate: 11.4% vs 111.5%
p-value: p=<0.0001
Left atrial diastolic dysfunction is present in patients with long-standing atrial fibrillation and pulmonary venous hypertension, potentially contributing to the pathophysiology of heart failure with preserved ejection fraction.
Heywood et al. (2014) conducted an observational in Atrial fibrillation and pulmonary venous hypertension (n=15). Atrial fibrillation and pulmonary venous hypertension vs. Pulmonary arterial hypertension and sinus rhythm was evaluated on Left atrial filling fraction (p=<0.0001). Patients with atrial fibrillation and pulmonary venous hypertension had markedly reduced left atrial filling fraction (11.4% vs 111.5%, p<0.0001) compared to those with pulmonary arterial hypertension.
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