Key result
Lone paroxysmal atrial fibrillation was associated with significantly lower active (P=0.009) and total (P=0.005) left atrial emptying fraction compared to healthy controls.
Why the study?
Does lone paroxysmal atrial fibrillation associate with structural and functional remodeling of the left atrium compared to healthy controls?
Case-Control (n=90)
Does lone paroxysmal atrial fibrillation associate with structural and functional remodeling of the left atrium compared to healthy controls?
p-value: p=0.009
Patients with lone paroxysmal atrial fibrillation exhibit structural and functional left atrial remodeling, suggesting the condition is associated with concealed cardiac dysfunction.
Authors
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May signal early LA impairment in lone PAF; leaves open causality and need for prospective validation.
Shin et al. (2010) conducted a case-control in Lone Paroxysmal Atrial Fibrillation (n=90). Lone Paroxysmal Atrial Fibrillation vs. Healthy controls was evaluated on Left atrial volume and left atrial emptying fraction (active, total, and passive) (p=0.009). Lone paroxysmal atrial fibrillation was associated with significantly lower active (P=0.009) and total (P=0.005) left atrial emptying fraction compared to healthy controls.