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April 25, 2025Cardiorenal MedicineOpen Access

Secondary Cardiorenal Syndromes in Children: Focus on Type 3 to 5 Cardiorenal Syndrome

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Why the study?

This review examines cardiovascular involvement in various nephrological diseases commonly seen in clinical practice, focusing on types 3-5 CRS in children from a nephrology perspective.

Population

Children with types 3-5 CRS or nephrological diseases

Design

Review

Key result

Cardiorenal syndrome types 3 to 5 in children pose a significant mortality risk, highlighting a critical need for longitudinal studies, specific biomarkers, and targeted therapies to improve outcomes.

Authors

ELEmre LeventoğluAKAkif KavgacıUÖUtku Arman Örün

Discussion

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Overview

High mortality in pediatric cardiorenal syndrome types 3-5 should not yet change practice; leaves open needs for longitudinal studies, biomarkers, and therapies.

Structured PICO

P
Population
Pediatric patients with cardiac, renal, or systemic conditions leading to cardiorenal syndrome (focus on types 3-5)

This review emphasizes the critical gaps in diagnosing and managing cardiorenal syndrome in pediatric patients, highlighting the need for new biomarkers and collaborative, large-scale studies.

Limitations

  • Lack of longitudinal studies or specific biomarkers for the diagnosis, treatment, and follow-up of CRS in children

Cite This Study

Leventoğlu et al. (2025) conducted a review in Cardiorenal syndrome (types 3-5). Cardiorenal syndrome types 3 to 5 in children pose a significant mortality risk, highlighting a critical need for longitudinal studies, specific biomarkers, and targeted therapies to improve outcomes.

synapsesocial.com/papers/6a0e56857b06478e784c2896https://doi.org/10.1159/000545791
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