Key result
Holter ECG analysis of 15 patients with prolonged RR intervals > 2.5 seconds revealed a paradoxically shortened QT interval in 2 cases, indicating abnormal repolarization adaptation.
Observational (n=15)
A paradoxically shortened QT interval during prolonged RR intervals was observed in a subset of patients, potentially indicating abnormal repolarization adaptation.
Alerts to possible repolarization anomalies during bradycardia; leaves open arrhythmic risk and need for validation.
We analyzed Holter ECG recordings in 15 patients with episodes of prolonged RR intervals > 2.5 seconds. In 13 patients, the QT interval showed a linear prolongation when RR interval was < 1.5 seconds and became relatively flat at longer RR intervals. In the remaining two patients, the QT and RR intervals were correlated within physiological range of RR intervals. However, at longer RR intervals, the QT interval was unexpectedly shortened and constant. The paradoxically shortened QT interval observed in the present 2 cases may indicate an abnormal adaptation of repolarization time to an abrupt increase in the preceding RR intervals.
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Takahashi et al. (1998) conducted an observational in Episodes of prolonged RR intervals > 2.5 seconds (n=15). Holter ECG analysis of 15 patients with prolonged RR intervals > 2.5 seconds revealed a paradoxically shortened QT interval in 2 cases, indicating abnormal repolarization adaptation.
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