Why the study?
Cases of paralytic polio prevented by investments in immunization programs and the Global Polio Eradication Initiative remained incompletely characterized.
Do polio vaccines and the GPEI prevent paralytic polio cases globally?
Comparison
Polio vaccines and GPEI vs counterfactual worlds without polio vaccines or GPEI
Design
Global transmission, immunity, and vaccine dynamics modeling study
Key result
Global use of polio vaccines prevented an estimated 29 million cases of paralytic polio between 1960 and 2021 compared to a counterfactual world with no polio vaccines.
Authors
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Supports sustained polio vaccination programs; extends prior models but leaves open precise future projections.
Do polio vaccines and the GPEI prevent paralytic polio cases globally?
Global modeling estimates that polio vaccines and the GPEI have prevented tens of millions of paralytic polio cases since 1960.
Badizadegan et al. (2022) studied Polio. Polio vaccines and Global Polio Eradication Initiative (GPEI) vs. Counterfactual world with no polio vaccines or without GPEI was evaluated on Number of paralytic polio cases prevented. Global use of polio vaccines prevented an estimated 29 million cases of paralytic polio between 1960 and 2021 compared to a counterfactual world with no polio vaccines.
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