Key result
Approaching heart failure with the methodology of systems biology and a biomechanical model promotes the elucidation of its complex pathophysiology and may lead to new therapeutic strategies.
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Supports systems biology in heart failure research; leaves open clinical translation pending prospective validation.
A systems biology approach integrating genes, molecules, and biomechanical models may help elucidate the complex pathophysiology of heart failure and identify new therapeutic strategies.
Louridas et al. (2012) conducted a review in Heart failure. Systems biology and biomechanical model was evaluated. Approaching heart failure with the methodology of systems biology and a biomechanical model promotes the elucidation of its complex pathophysiology and may lead to new therapeutic strategies.
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