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January 20, 2015Congenital Heart Disease

None of the ECG parameters showed significant correlation with 2D-LVM z-scores; R in V6 voltages showed sensitivity 13-29%, specificity 77-96%, PPV 29-50%, and NPV 77%.

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Why the study?

Does the electrocardiogram accurately detect left ventricular hypertrophy compared to echocardiography in children?

Population

250 children and young adults with complete 2D-LVM measurements, temporally matched ECGs, and no confounding…

Comparison

Electrocardiogram assessment for left… vs Echocardiographic two-dimensional left…

Design

Cross-sectional

Authors

ABAndrás BratincsákMWMatthew R. WilliamsCKChieko Kimata

Discussion

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Overview

ECG lacks accuracy for LVH detection in children; leaves open need for reliable noninvasive markers.

Structured PICO

Does the electrocardiogram accurately detect left ventricular hypertrophy compared to echocardiography in children?

P
Population
250 children and young adults with complete 2D-LVM measurements, temporally matched ECGs, and no confounding structural heart defects
I
Intervention
Electrocardiogram (ECG) assessment for left ventricular hypertrophy using pediatric datasets (Davignon, Macfarlane, Rijnbeek) and adult indices (Sokolow-Lyon, Cornell, Gubner, Romhilt-Estes)
C
Comparator
Echocardiographic two-dimensional left ventricular mass (2D-LVM) assessment (LVH defined as z-score > 2)
O
Outcome
Diagnostic accuracy (sensitivity, specificity, PPV, NPV, overall accuracy) of ECG parameters for detecting LVHsurrogate

The ECG is an unreliable screening tool for detecting left ventricular hypertrophy in children due to its poor sensitivity and positive predictive value compared to echocardiography.

Cite This Study

Bratincsák et al. (2015) studied this question.

synapsesocial.com/papers/6a0e9cd89504565763479d07https://doi.org/10.1111/chd.12249
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Electrocardiographic Criteria for Left Ventricular Hypertrophy in Children2008 · 45 citations
  2. 2Are Electrocardiographic Criteria Reliable for Left Ventricular Hypertrophy Detection in Indian Adults?2023 · 1 citations
  3. 3Assessment of Left Ventricular Hypertrophy in Patients With Essential Hypertension A Rational Basis for the Electrocardiogram1993 · 27 citations
  4. 4ECG is an inefficient screening-tool for left ventricular hypertrophy in normotensive African children population2016 · 1 citations
  5. 5Accuracy of the Electrocardiograph in Detecting Cardiac Left Ventricular Hypertrophy in Pediatric Patients with Aortic Valve Disease2015