April 24, 2008Pediatric CardiologyOpen Access

At 95% specificity, the best single pediatric ECG criterion (SV3R + RV7) had a sensitivity of 25.3% for detecting left ventricular hypertrophy based on mass index alone, which improved to 51.3% when combining two ECG parameters and clinical evidence.

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Left ventricular hypertrophy (n=832). Intervention: Electrocardiogram (ECG) criteria vs. Echocardiographic left ventricular mass index (LVMI). Primary outcome: Sensitivity of ECG criteria for detecting LVH at 95% specificity.

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Why the study?

What is the sensitivity of 12-lead ECG criteria for detecting left ventricular hypertrophy in children compared to echocardiographic left ventricular mass index?

Population

832 children who had a 12-lead ECG and an M-mode echocardiogram taken on the same day

Comparison

12-lead ECG criteria for left ventricular… vs Abnormal left ventricular mass index derived…

Design

Cross-sectional

Key result

At 95% specificity, the best single pediatric ECG criterion (SV3R + RV7) had a sensitivity of 25.3% for detecting left ventricular hypertrophy based on mass index alone, which improved to 51.3% when combining two ECG parameters and clinical evidence.

Authors

PRPeter R. Rijnbeek GHGerard van Herpen LKLivia Kapusta

Discussion

Member takes

Overview

May refine pediatric ECG criteria for LVH; leaves open validation against comprehensive clinical standards.

Study Design

Type

Cross-Sectional (n=832)

Multicenter

Structured PICO

What is the sensitivity of 12-lead ECG criteria for detecting left ventricular hypertrophy in children compared to echocardiographic left ventricular mass index?

Population

832 children aged 0 to 15 years who underwent simultaneous 12-lead ECG and M-mode echocardiography to evaluate the diagnostic sensitivity of ECG criteria for left ventricular hypertrophy.

Exposure

12-lead ECG criteria for left ventricular hypertrophy (based on age-dependent normal limits)

Comparator

Abnormal left ventricular mass (LVM) index derived from M-mode echocardiogram, either alone or in combination with other clinical evidence

Outcome

Sensitivity of ECG criteria for detecting left ventricular hypertrophy at 95% specificitysurrogate

The pediatric 12-lead ECG has low sensitivity for detecting left ventricular hypertrophy, though diagnostic performance improves when combined with clinical evidence.

Limitations

Validated using M-mode echocardiography rather than cardiac MRI.
Use of V3R and V7 leads instead of standard V3 and V5 makes comparison with other studies difficult.
Unable to determine the effect of concomitant right ventricular hypertrophy due to low case numbers.
Limited sample size prevented establishing the effect of gender on ECG criteria.

Cite This Study

Rijnbeek et al. (2008) conducted a cross-sectional in Left ventricular hypertrophy (n=832). Electrocardiogram (ECG) criteria vs. Echocardiographic left ventricular mass index (LVMI) was evaluated on Sensitivity of ECG criteria for detecting LVH at 95% specificity. At 95% specificity, the best single pediatric ECG criterion (SV3R + RV7) had a sensitivity of 25.3% for detecting left ventricular hypertrophy based on mass index alone, which improved to 51.3% when combining two ECG parameters and clinical evidence.

synapsesocial.com/papers/6a51a0bfccac8b7790d5bc34 https://doi.org/10.1007/s00246-008-9235-y

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April 24, 2008Pediatric CardiologyOpen Access

At 95% specificity, the best single pediatric ECG criterion (SV3R + RV7) had a sensitivity of 25.3% for detecting left ventricular hypertrophy based on mass index alone, which improved to 51.3% when combining two ECG parameters and clinical evidence.

View Full Paper

Ask AI

Bookmark

Why the study?

What is the sensitivity of 12-lead ECG criteria for detecting left ventricular hypertrophy in children compared to echocardiographic left ventricular mass index?

Population

832 children who had a 12-lead ECG and an M-mode echocardiogram taken on the same day

Comparison

12-lead ECG criteria for left ventricular… vs Abnormal left ventricular mass index derived…

Design

Cross-sectional

Key result

Authors

PRPeter R. Rijnbeek GHGerard van Herpen LKLivia Kapusta

Discussion

Member takes

Overview

May refine pediatric ECG criteria for LVH; leaves open validation against comprehensive clinical standards.

Study Design

Type

Cross-Sectional (n=832)

Multicenter

Structured PICO

What is the sensitivity of 12-lead ECG criteria for detecting left ventricular hypertrophy in children compared to echocardiographic left ventricular mass index?

Population

832 children aged 0 to 15 years who underwent simultaneous 12-lead ECG and M-mode echocardiography to evaluate the diagnostic sensitivity of ECG criteria for left ventricular hypertrophy.

Exposure

12-lead ECG criteria for left ventricular hypertrophy (based on age-dependent normal limits)

Comparator

Abnormal left ventricular mass (LVM) index derived from M-mode echocardiogram, either alone or in combination with other clinical evidence

Outcome

Sensitivity of ECG criteria for detecting left ventricular hypertrophy at 95% specificitysurrogate

The pediatric 12-lead ECG has low sensitivity for detecting left ventricular hypertrophy, though diagnostic performance improves when combined with clinical evidence.

Limitations

Validated using M-mode echocardiography rather than cardiac MRI.
Use of V3R and V7 leads instead of standard V3 and V5 makes comparison with other studies difficult.
Unable to determine the effect of concomitant right ventricular hypertrophy due to low case numbers.
Limited sample size prevented establishing the effect of gender on ECG criteria.

Cite This Study

synapsesocial.com/papers/6a51a0bfccac8b7790d5bc34 https://doi.org/10.1007/s00246-008-9235-y

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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