Key result
Pulmonary valve autotransplantation (the Ross operation) performed in 249 patients over 20 years resulted in a 6.5% operative mortality rate and a 14.4% reoperation rate.
Why the study?
What are the long-term outcomes and survival rates of pulmonary valve autotransplantation (the Ross Operation)?
Cohort (n=249)
What are the long-term outcomes and survival rates of pulmonary valve autotransplantation (the Ross Operation)?
The Ross Operation demonstrates excellent long-term viability of the autograft in the aortic position with no primary tissue failure, though reoperations remain a consideration.
Answers are grounded in this paper and cite their sources.
May inform Ross procedure counseling in select patients; leaves open need for randomized comparisons.
In 1967, homografts had been in place five years and the early nonviable and natant freeze-dried valves were showing irrefutable signs of degeneration and calcification. For this reason, in 1967, we moved to reserving both viability and tissue integrity by cryopreservation. To overcome the problems of procurement, the next logical step was to transfer the patient's own pulmonic valve to the aortic area. In the past twenty years, 249 operations have been performed. Of the 249 patients, there have been 16 operative deaths (6.5%), but no operative deaths in the past ten years. There have been no details related to primary tissue failure in the aortic area. There have been 36 reoperations (14.4%).
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Donald Ross (1988) conducted a cohort in Aortic valve disease requiring replacement (n=249). Pulmonary valve autotransplantation (The Ross Operation) was evaluated on Operative deaths. Pulmonary valve autotransplantation (the Ross operation) performed in 249 patients over 20 years resulted in a 6.5% operative mortality rate and a 14.4% reoperation rate.
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