Key result
Heart failure progression shares multiple molecular signaling pathways with cancer biology, suggesting that targeted therapies addressing specific phenotypic endpoints and molecular checkpoints may offer new treatment strategies.
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Discusses the shared features of organ size, shape, and histological phenotype changes in tumorigenesis and heart failure.
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Hoshijima et al. (2002) conducted a review in Heart failure. Heart failure progression shares multiple molecular signaling pathways with cancer biology, suggesting that targeted therapies addressing specific phenotypic endpoints and molecular checkpoints may offer new treatment strategies.
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