Key result
Termination of electrically induced atrial fibrillation usually occurs abruptly to sinus rhythm without progressive organization or a required decrease in atrial rate.
Why the study?
What are the electrophysiological changes immediately prior to the termination of electrically induced atrial fibrillation in humans?
Population
14 patients with electrically induced atrial fibrillation
Design
Cohort
Authors
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Challenges progressive organization models of AF termination; hypothesis-generating and leaves open applicability to spontaneous AF.
Observational (n=14)
What are the electrophysiological changes immediately prior to the termination of electrically induced atrial fibrillation in humans?
The abrupt termination of atrial fibrillation without preceding organization or stabilization of wavefronts suggests simultaneous block of all wavelets rather than progressive fusion as the mechanism of termination.
Sih et al. (1994) conducted an observational in Atrial fibrillation (n=14). Procainamide-induced termination vs. Spontaneous termination was evaluated on Atrial rate, mean magnitude squared coherence, and direction of activation prior to termination. Termination of electrically induced atrial fibrillation usually occurs abruptly to sinus rhythm without progressive organization or a required decrease in atrial rate.
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