Key result
Teleprehabilitation before CABG fails to delay worsening cardiac symptoms compared to standard care.
Why the study?
It was unclear whether teleprehabilitation leads to worsening cardiac symptoms in patients awaiting CABG.
Does teleprehabilitation lead to worsening cardiac symptoms in patients accepted for CABG?
RCT (n=155)
Randomized
Does teleprehabilitation lead to worsening cardiac symptoms in patients accepted for CABG?
p-value: p=0.529
Teleprehabilitation, including low-intensity physical training, does not lead to worsening cardiac symptoms prior to elective CABG and can be safely offered.
No increase in cardiac symptoms with teleprehabilitation before CABG; supports safe adoption and extends RCT evidence for remote prehabilitation.
Aims The purpose of this subanalysis is to explore whether or not teleprehabilitation leads to worsening cardiac symptoms in patients accepted for coronary artery bypass grafting (CABG). Methods A subgroup of patients accepted for CABG (including off-pump and minimally invasive) who were randomised between teleprehabilitation and standard care in DCC-trial were included. Prehabilitation patients had access to blended care supported by online modules, including nutritional support, functional exercise training, smoking cessation, inspiratory muscle training, and psychological support. All patients were weekly telemonitored for cardiac symptoms using a customized digital platform. Results This cohort included 155 patients. Baseline characteristics, including NYHA and CCS class, were balanced, except for shorter preoperative waiting times in weeks (15.0 [9.8-22.2] versus 12.5 [7.0-16.0]) in the teleprehabilitation group. There was no significant difference in incidence of major adverse cardiac events in the preoperative period. There were 141 patients (77 control; 64 teleprehabilitation) with at least one symptom monitoring entry. A total of 373/1786 (21%) entries indicated worsening of cardiac symptoms. The distribution was right-skewed and did not significantly differ between both groups. There was no statistically significant difference in time to event between control and teleprehabilitation for any cardiac symptom (p = 0.529), angina (p = 0.167), or dyspnea (p = 0.334). Conclusion Teleprehabilitation does not lead to worsening cardiac symptoms prior to CABG. We postulate that teleprehabilitation, which includes low-intensity physical training, can be safely offered to patients undergoing elective CABG.
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Susante et al. (2026) conducted an RCT in Patients accepted for coronary artery bypass grafting (CABG) (n=155). Teleprehabilitation vs. Standard care was evaluated on Time to event for any cardiac symptom (p=0.529). Teleprehabilitation prior to CABG did not significantly differ from standard care in time to worsening of any cardiac symptom (p=0.529), angina (p=0.167), or dyspnea (p=0.334).
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