Key result
Analysis of interectopic continuous electrical activity in dogs with myocardial infarction revealed that sustained ventricular tachycardia is maintained by slow conduction within a reentrant circuit.
In a canine model of myocardial infarction, sustained ventricular tachycardia is maintained by slow conduction in a reentrant circuit, which can be localized and modulated by pacing and procainamide.
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Supports reentry mechanism for post-MI VT in canine model; leaves open human translation and therapeutic targeting.
Brachmann et al. (1983) studied Sustained ventricular tachycardia (n=24). Ventricular pacing and Procainamide was evaluated on Patterns of interectopic continuous electrical activity. Analysis of interectopic continuous electrical activity in dogs with myocardial infarction revealed that sustained ventricular tachycardia is maintained by slow conduction within a reentrant circuit.
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