Key result
Catheter ablation cuts tachycardia cardioversion admissions by ~100% vs antiarrhythmic drugs over 5 years.
Why the study?
Does catheter ablation reduce hospital admission for persistent tachycardia cardioversion in patients with symptomatic AVNRT compared to antiarrhythmic drug therapy?
Population
61 patients with at least one symptomatic episode of tachycardia per month and an electrophysiologic…
Comparison
Catheter ablation vs Chronic antiarrhythmic drug therapy with…
Design
RCT, randomly assigned
Follow-up
5 years
Authors
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Supports preferring ablation to avoid hospitalizations in symptomatic AVNRT; confirms long-term superiority over AAD in this RCT.
RCT (n=61)
Does catheter ablation reduce hospital admission for persistent tachycardia cardioversion in patients with symptomatic AVNRT compared to antiarrhythmic drug therapy?
Absolute Event Rate: 0% vs 67.7%
p-value: p=<0.001
Catheter ablation significantly reduces the need for hospital admission for cardioversion compared to antiarrhythmic drug therapy in patients with symptomatic AVNRT.
Katritsis et al. (2016) conducted an RCT in symptomatic atrioventricular nodal re-entrant tachycardia (AVNRT) (n=61). Catheter ablation vs. Chronic antiarrhythmic drug (AAD) therapy with bisoprolol (5 mg od) and/or diltiazem (120-300 mg od) was evaluated on Hospital admission for persistent tachycardia cardioversion (p=<0.001). Catheter ablation significantly reduced hospital admissions for persistent tachycardia cardioversion compared to antiarrhythmic drug therapy (0% vs 67.7%; P<0.001) over 5 years.
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