Key result
Hospital management of incident HF linked to ~292% higher 1-year mortality versus primary care.
Why the study?
Heart failure patients managed in primary care and hospital care may differ in demography, comorbidities, and outcomes.
Does management setting (hospital care vs primary care) affect one-year mortality in patients with incident heart failure?
Observational (n=35,375)
Yes
Does management setting (hospital care vs primary care) affect one-year mortality in patients with incident heart failure?
Effect estimate: HR 3.92 (95% CI 3.77-4.08)
p-value: p=<0.0001
Heart failure patients managed in hospital care have significantly higher 1-year mortality compared to those managed in primary care, likely reflecting differences in patient demographics, comorbidities, and disease severity.
Should not prompt avoidance of hospital care for incident HF; leaves open confounding by indication in observational data.
Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)-based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden. Methods The VEGA database is an administrative database that includes all patients living in VGR. Patients with a first principal or contributory diagnosis of HF (I50) ≥18 years old between 2008 and 2017 were included. One-year mortality was used as the outcome. Results In total, 35 375 new-onset HF cases were included with 18 722 identified only in PC and 16 651 in HC. HF patients in PC were older (80.7 ± 10.9 vs. 76.1 ± 13.6), more women (57.1% vs. 44.9%), with more hypertension, musculoskeletal and mental disorders, but less myocardial infarction. Patients in HC had almost 4 times higher all-cause 1 year mortality [3.92 (3.77–4.08), P < 0.0001] compared with PC after adjustment for age and sex. Over a 10 year period, despite decreasing mortality in both settings, hazard ratios for HC versus PC were significantly increased for all patients (P for interaction 0.0004), which was more marked in female and for 70–80 years old patients. Conclusion Over a 10 year period, we demonstrated the differences in demography, comorbidities and outcomes between heart failure patients managed in hospital care versus primary care.
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Chen et al. (2024) conducted an observational in Incident Heart Failure (n=35,375). Hospital care vs. Primary care was evaluated on One-year mortality (HR 3.92, 95% CI 3.77-4.08, p=<0.0001). Hospital care management of incident heart failure was associated with higher 1-year all-cause mortality compared with primary care management (HR 3.92; 95% CI 3.77-4.08; P<0.0001).
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