Key result
CMR global radial peak strain distinguishes subclinical HCM from subclinical HHD with ~0.89 AUC.
Why the study?
The evaluation of cardiac magnetic resonance feature tracking may have diagnostic value in hypertrophic cardiomyopathy and hypertension heart disease, prompting exploration of its value in evaluating myocardial deformation in subclinical disease.
Does cardiac magnetic resonance feature tracking differentiate subclinical hypertrophic cardiomyopathy from subclinical hypertension heart disease?
Cross-Sectional (n=91)
No
Does cardiac magnetic resonance feature tracking differentiate subclinical hypertrophic cardiomyopathy from subclinical hypertension heart disease?
CMR feature tracking, specifically global radial peak strain, can effectively differentiate subclinical hypertrophic cardiomyopathy from subclinical hypertensive heart disease before routine cardiac function parameters become abnormal.
May aid differentiation of subclinical hypertrophic cardiomyopathy from hypertensive heart disease; hypothesis-generating and requires prospective validation.
The evaluation of cardiac magnetic resonance feature tracking may have great diagnostic value in hypertrophic cardiomyopathy and hypertension heart disease.To explore the diagnostic and clinical research value of cardiac magnetic resonance feature tracking in evaluation of myocardium deformation in patients with subclinical hypertrophic cardiomyopathy(SHCM)and subclinical hypertension heart disease(SHHD).CMR scans was performed on 1.5 T MR scanner in 33 patients with SHCM,31 patients with SHHD, and 27 controls(NS).The CMR image post-processing software was used to analyze the characteristics of routine cardiac function, different global and regional myocardial strain in each group.Analysis of variance (ANOVA) was used to compare age, blood pressure,heart rate,routine cardiac function,body mass index (BMI), as well as the strain between different segments within each of the three groups. If a significant difference was detected, a least significant difference (LSD) comparison was performed if there was a significant difference.The diagnostic efficacy of different parameters in differentiating SHHD from SHCM was evaluated through receiver operating characteristic (ROC) curve analysis, and determination of the best cutoff value.The routine cardiac function parameters were no statistically different among three groups ( P ＞0.05).There are statistical differences between the global myocardial strain parameters and the peak strain parameters of some segments,especially the basal segment, in each group ( P ＜0.05), and the Global radial peak strain(GRPS) can be used to distinguish SHCM from SHHD group (The area under the ROC curve was 0.885), which is the best diagnostic performance.Cardiac magnetic resonance feature tracking can detect left ventricular deformation in patients with SHCM and SHHD group.The abnormality of strain has important research value for its subclinical diagnosis and clinical evaluation.
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Hao et al. (2023) conducted a cross-sectional in Subclinical Hypertrophic Cardiomyopathy and Subclinical Hypertension Heart Disease (n=91). Cardiac Magnetic Resonance Feature Tracking (CMR-FT) vs. Normal subjects was evaluated on Diagnostic efficacy of Global Radial Peak Strain (GRPS) in differentiating SHHD from SHCM (AUC 0.885, 95% CI 0.805-0.964). Global radial peak strain measured by cardiac magnetic resonance feature tracking effectively distinguished subclinical hypertrophic cardiomyopathy from subclinical hypertension heart disease with an AUC of 0.885.
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