Key result
Essential hypertension is linked to ~17% lower global radial strain despite normal LVEF.
Why the study?
The study sought to identify subclinical global systolic function abnormalities and evaluate influencing factors associated with LV strain parameters in hypertensive patients using CMR-FT.
Does CMR-FT detect subclinical global systolic function abnormalities in patients with essential hypertension compared to healthy volunteers?
Population
57 patients with essential hypertension and 26 healthy volunteers
Comparison
Patients with essential hypertension vs healthy volunteers
Authors
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Supports CMR-FT for subclinical dysfunction detection in hypertension; hypothesis-generating and needs prospective validation before clinical use.
Case-Control (n=83)
Single-blind
No
Does CMR-FT detect subclinical global systolic function abnormalities in patients with essential hypertension compared to healthy volunteers?
Absolute Event Rate: 35.14% vs 42.14%
p-value: p=<0.001
CMR-FT can detect early subclinical myocardial damage in essential hypertension patients before ejection fraction abnormalities occur.
Liu et al. (2020) conducted a case-control in Essential Hypertension (n=83). Essential hypertension vs. Healthy volunteers was evaluated on Global radial strain (GRS) (p=<0.001). Patients with essential hypertension had significantly impaired myocardial deformation, including reduced global radial strain (35.14% vs 42.14%), compared to healthy controls despite normal ejection fraction.
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