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July 23, 2018EP Europace31 citationsOpen Access

Advancement in cardiac imaging for treatment of ventricular arrhythmias in structural heart disease

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MŠMarek ŠramkoJHJarieke C. HoogendoornCGClaire A. Glashan

Key Result

Advanced cardiac imaging provides valuable adjunctive information to conventional electroanatomical mapping to delineate scar and facilitate ventricular tachycardia ablation in structural heart disease.

Key Points

  • Review the histological validation and clinical utility of cardiac imaging and electroanatomical mapping for identifying arrhythmogenic substrate in structural heart disease.
  • Reviewed histological characteristics of structural heart disease etiologies associated with monomorphic sustained ventricular tachycardia.
  • Assessed data validating cardiac imaging modalities and electroanatomical mapping against histology for three-dimensional scar characterization.
  • Conventional electroanatomical mapping exhibits key limitations in resolving complex, three-dimensional scar architecture.
  • Advanced cardiac imaging modalities offer critical adjunctive anatomical detail to better define the arrhythmogenic substrate and facilitate safer, more effective ablation procedures.

Structured PICO

Do advanced cardiac imaging technologies improve the safety and efficacy of catheter ablation for ventricular tachycardia in patients with structural heart disease?

P
Population
Patients with structural heart disease (SHD) and unmappable ventricular tachycardia (VT)
I
Intervention
Advanced cardiac imaging technologies as an adjunct to conventional electroanatomical mapping (EAM) for VT ablation
O
Outcome
Safety and efficacy of catheter ablation

Advanced cardiac imaging provides valuable adjunctive information to conventional electroanatomical mapping for delineating scar and arrhythmogenic substrate during VT ablation.

Abstract

Over the last decades, substrate-based approaches to ventricular tachycardia (VT) ablation have evolved into an important therapeutic option for patients with various structural heart diseases (SHD) and unmappable VT. The well-recognized limitations of conventional electroanatomical mapping (EAM) to delineate the complex 3D architecture of scar, and the potential capability of advanced cardiac imaging technologies to provide adjunctive information, have stimulated electrophysiologists to evaluate the role of imaging to improve safety and efficacy of catheter ablation. In this review, we summarize the histological differences between SHD aetiologies related to monomorphic sustained VT and the currently available data on the histological validation of cardiac imaging modalities and EAM to delineate scar and the arrhythmogenic substrate. We review the current evidence of the value provided by cardiac imaging to facilitate VT ablation and to ultimately improve outcome.

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Cite This Study

Šramko et al. (2018) conducted a review in Ventricular tachycardia in structural heart disease. Advanced cardiac imaging vs. Conventional electroanatomical mapping was evaluated. Advanced cardiac imaging provides valuable adjunctive information to conventional electroanatomical mapping to delineate scar and facilitate ventricular tachycardia ablation in structural heart disease.

synapsesocial.com/papers/6a0eaf0b8da6dd046147a4d1https://doi.org/10.1093/europace/euy150
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