January 1, 1990American Journal of Epidemiology
The Epidemiology of Idiopathic Dilated Cardiomyopathy in a Biracial Community
Key result
Black race was independently associated with an increased risk of idiopathic dilated cardiomyopathy (OR 2.7; 95% CI 2.0-3.4; p<0.05), alongside low annual income and a history of asthma.
Why the study?
Are black race, low income, and history of asthma associated with an increased risk of idiopathic dilated cardiomyopathy?
Population
190 individuals, matched on sex and 5-year age intervals.
Design
Case-control
Authors
Discussion
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Implication
Supports investigation of racial and socioeconomic disparities in idiopathic dilated cardiomyopathy; should not yet change practice.
Study Design
Type
Case-Control (n=190)
Multicenter
Yes
Structured PICO
Are black race, low income, and history of asthma associated with an increased risk of idiopathic dilated cardiomyopathy?
P
Population
190 individuals (95 newly diagnosed cases of idiopathic dilated cardiomyopathy from four Baltimore hospitals and 95 neighborhood controls), matched on sex and 5-year age intervals.
O
Outcome
Association of idiopathic dilated cardiomyopathy with black race and other genetic and environmental factors
Main Result
Effect estimate: OR 2.7 (95% CI 2.0-3.4)
p-value: p=<0.05
Black race, low annual income, and a history of asthma are significant independent risk factors for idiopathic dilated cardiomyopathy.
Cite This Study
Coughlin et al. (1990) conducted a case-control in Idiopathic dilated cardiomyopathy (n=190). Risk factors (black race, low income, asthma) vs. Neighborhood controls was evaluated on Idiopathic dilated cardiomyopathy (OR 2.7, 95% CI 2.0-3.4, p=<0.05). Black race was independently associated with an increased risk of idiopathic dilated cardiomyopathy (OR 2.7; 95% CI 2.0-3.4; p<0.05), alongside low annual income and a history of asthma.