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April 16, 2019Proceedings of the National Academy of SciencesOpen Access

Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

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LZLei ZhangJiangsu UniversityXDXiao DongUniversity of MinnesotaMLMoonsook LeeAlbert Einstein College of Medicine

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Zhang et al. (2019) studied this question.

synapsesocial.com/papers/6a0ec14625c30b2cc7f9bd3fhttps://doi.org/10.1073/pnas.1902510116
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mutation of BCL-6 Gene in Normal B Cells by the Process of Somatic Hypermutation of Ig Genes1998 · 540 citations
  2. 2Predicting the Functional Effect of Amino Acid Substitutions and Indels2012 · 3,054 citations
  3. 3Collagen receptor on T lymphocytes and the control of lymphocyte motility1989 · 40 citations
  4. 4Evidence for mutation showers2007 · 76 citations