Key result
Higher depressed mood scores were significantly associated with higher 24-hour ambulatory blood pressure in subjects with a family history of hypertension, but not in those without.
Why the study?
Does depressed mood associate with higher ambulatory blood pressure in individuals with a family history of hypertension?
Cross-Sectional (n=314)
Does depressed mood associate with higher ambulatory blood pressure in individuals with a family history of hypertension?
Depressed mood is associated with higher ambulatory blood pressure specifically in individuals with a family history of hypertension, suggesting an underlying susceptibility is required for this effect.
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Supports familial susceptibility to mood-BP effects; hypothesis-generating and requires prospective studies before any clinical consideration.
Grewen et al. (2004) conducted a cross-sectional in Family history of hypertension (n=314). Depressed mood (Beck Depression Inventory score) vs. Subjects without a family history of hypertension (FH-) was evaluated on 24-hour ambulatory blood pressure. Higher depressed mood scores were significantly associated with higher 24-hour ambulatory blood pressure in subjects with a family history of hypertension, but not in those without.
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