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September 3, 2002CirculationOpen Access

Segmental Ostial Ablation to Isolate the Pulmonary Veins During Atrial Fibrillation

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Why the study?

Does segmental ostial ablation during atrial fibrillation achieve comparable pulmonary vein isolation compared to ablation during sinus rhythm in patients with AF?

Population

40 consecutive patients undergoing pulmonary vein isolation for atrial fibrillation, with 125 PVs targeted…

Comparison

Segmental pulmonary vein ostial ablation… vs Segmental pulmonary vein ostial ablation…

Design

Cohort

Key result

Segmental ostial ablation during atrial fibrillation achieved complete pulmonary vein isolation in 100% of targeted veins compared to 96% during sinus rhythm (P=0.4).

Authors

HOHakan OralBKBradley P. KnightMÖMehmet Özaydın

Discussion

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Overview

Supports AF-guided ablation with comparable isolation; leaves open randomized outcome trials before practice change.

Study Design

Type

Observational (n=40)

Structured PICO

Does segmental ostial ablation during atrial fibrillation achieve comparable pulmonary vein isolation compared to ablation during sinus rhythm in patients with AF?

P
Population
40 consecutive patients undergoing pulmonary vein (PV) isolation for atrial fibrillation (AF), with 125 PVs targeted for isolation.
I
Intervention
Segmental pulmonary vein (PV) ostial ablation performed during atrial fibrillation (AF) guided by PV tachycardia (70 veins)
C
Comparator
Segmental pulmonary vein (PV) ostial ablation performed during sinus rhythm guided by PV potentials (55 veins)
O
Outcome
Complete PV isolationsurrogate

Main Result

Absolute Event Rate: 100% vs 96%

p-value: p=0.4

Segmental ostial ablation guided by PV tachycardia during AF is feasible and achieves similar isolation rates as ablation during sinus rhythm, supporting the role of PV tachycardias in AF perpetuation.

Cite This Study

Oral et al. (2002) conducted an observational in Atrial fibrillation (n=40). Segmental pulmonary vein ostial ablation during atrial fibrillation vs. Segmental pulmonary vein ostial ablation during sinus rhythm was evaluated on Complete pulmonary vein isolation (p=0.4). Segmental ostial ablation during atrial fibrillation achieved complete pulmonary vein isolation in 100% of targeted veins compared to 96% during sinus rhythm (P=0.4).

synapsesocial.com/papers/6a0eca0406ecbe833447cdadhttps://doi.org/10.1161/01.cir.0000027821.55835.00
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