Key result
Reversed-phase HPLC method for Rivaroxaban demonstrates high linearity with a 0.999 correlation coefficient.
Population
Rivaroxaban in raw materials
Design
Analytical method development and validation study
Authors
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May support rivaroxaban quality control; leaves open clinical pharmacokinetic validation.
A robust and precise RP-HPLC method was successfully developed and validated for the quality control analysis of rivaroxaban in raw materials and finished products.
Aktham Mestareehi (2025) studied this question. Reversed-phase high-performance liquid chromatography (RP-HPLC) was evaluated on Linearity and method validation. A reversed-phase high-performance liquid chromatography method for Rivaroxaban demonstrated linearity in the concentration range of 50 to 1,000 ppm with a correlation coefficient of 0.999.
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