Key result
Wall motion index provided significant independent prognostic information on 2-year survival in heart failure patients, with survival ranging from 39.9% to 90.7% based on WMI and NYHA class.
Why the study?
Does echocardiographic wall motion index predict survival in patients with chronic congestive heart failure?
Cohort (n=190)
No
Does echocardiographic wall motion index predict survival in patients with chronic congestive heart failure?
Echocardiographic wall motion index provides significant independent prognostic value for 2-year survival in patients with chronic congestive heart failure, which is further improved by adding LVEF.
WMI may refine HF prognosis beyond NYHA; leaves open incremental value over LVEF for guiding care.
Survival in 190 consecutive patients with congestive heart failure, discharged from a general hospital, was studied. Sixteen patients were in New York Heart Association (NYHA) class I, 87 in II, 83 in III and 4 in IV. Median left ventricular ejection fraction (LVEF) from radionuclide ventriculography was 0.30 (range 0.06-0.74). Two-year survival was 68%. Wall motion index was the only echocardiographic variable with significant, independent, prognostic information on survival. The 2-year survival in NYHA classes I and II was 90.7% for wall motion index > or = 1.3, and 78.6% when < 1.3. In classes III and IV survival was 68.9% for wall motion index > or = 1.3 and 39.9% when < 1.3. Addition of LVEF gave further information about survival. This study demonstrates that echocardiography is of great value in determining prognosis in congestive heart failure patients, and that wall motion index contains the majority of the information. Wall motion index is closely correlated to LVEF, however prognostication is improved when information about LVEF is added.
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Madsen et al. (2008) conducted a cohort in Chronic Congestive Heart Failure (n=190). Echocardiography (Wall motion index) was evaluated on 2-year survival. Wall motion index provided significant independent prognostic information on 2-year survival in heart failure patients, with survival ranging from 39.9% to 90.7% based on WMI and NYHA class.
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