Why the study?
Whether linear ablation should be performed for persistent AF remains controversial, and the efficacy and safety of AI-guided high-energy linear ablation of the mitral isthmus and LA posterior wall are unclear.
Does PVI combined with AI-guided high-power linear ablation of the mitral isthmus and left atrial posterior wall prevent arrhythmia recurrence in patients with persistent atrial fibrillation?
Population
200 consecutive PAF patients
Comparison
PVI combined with AI-guided high-power linear ablation of LAPWI and MI
Design
Single-arm prospective study
Follow-up
Average 24 months
Key result
Pulmonary vein isolation combined with ablation index-guided high-power linear ablation of the mitral isthmus and posterior box isolation achieved an 87.5% freedom from atrial arrhythmia in patients with persistent atrial fibrillation.
Authors
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May support this ablation strategy in persistent AF; hypothesis-generating and requires randomized confirmation.
Observational (n=200)
No
Does PVI combined with AI-guided high-power linear ablation of the mitral isthmus and left atrial posterior wall prevent arrhythmia recurrence in patients with persistent atrial fibrillation?
PVI combined with AI-guided high-power linear ablation of the mitral isthmus and posterior box is a feasible and effective strategy for persistent atrial fibrillation, achieving an 87.5% freedom from arrhythmia at 20 months.
Li et al. (2022) conducted an observational in Persistent atrial fibrillation (n=200). Pulmonary vein isolation (PVI) plus AI-guided high-power linear ablation of mitral isthmus and posterior box isolation was evaluated on Freedom from atrial fibrillation or atrial tachycardia. Pulmonary vein isolation combined with ablation index-guided high-power linear ablation of the mitral isthmus and posterior box isolation achieved an 87.5% freedom from atrial arrhythmia in patients with persistent atrial fibrillation.